Histamine Dump at Night Symptoms A condition often referred to as a “histamine dumping,” occurs when there’s an excessive release of histamine (a naturally occurring compound involved in immune responses, digestion, sleep regulation, and even cardiovascular system) or when there is a deficiency of diamine oxidase (DAO), an enzyme that breaks down histamine. While histamine […]
COMT Gene Mutation Supplements To understand COMT Gene Mutation Supplements, it’s important to first know the COMT gene and its mutation. The COMT (catechol-O-methyltransferase) gene encodes an enzyme (COMT enzyme) responsible for breaking down catecholic compounds in the body, including neurotransmitters like dopamine, norepinephrine, and epinephrine, as well as hormones such as estrogen. By methylating […]
Pharmacogenetic Testing Costs in the USA The Pharmacogenetic Testing Costs vary based on the test complexity and insurance coverage. Some medications, especially mental health ones, have been indicated by the FDA to be administered based on genetic profile, which is commonly known as genome-based medication. Thus, depending on the issues an individual is experiencing, Medicare […]
What Is Gene Sight Testing? Pros, Cons, and More Pharmacogenomic testing, also known as PGx testing, gives insights into your genetic makeup. In case of certain medications, this information is utilised to tailor treatments that have the least chance of trial and error. GeneSight testing is a branch of pharmacogenomic testing that assists healthcare providers […]
Hormonal imbalances can significantly impact overall health, affecting everything from energy levels to mood and metabolism. The blood tests in this regard provide insights into hormone function, however, these tests require you to visit your healthcare specialist and are not non-invasive. The DUTCH testing, in comparison, has a different approach that offers a comprehensive analysis […]
OCD vs Anxiety: Symptoms, Medication, and More Obsessive-Compulsive Disorder (OCD) and anxiety disorders are two of the most common mental health conditions in the United States. Although they share some similarities, they differ significantly in symptoms, causes, and treatment approaches. Anxiety disorders involve excessive worry, fear, or nervousness that interfere with daily life. Common types […]
What is Metformin Used for Typically? Primarily used to treat Type 2 diabetes, Metformin has shown positive results in treating Polycystic Ovary Syndrome (PCOS), which is a major cause of infertility. Available under different brand names, in different potencies, with immediate release and extended release (XR) options, this drug is administered differently to patients based […]
COMT Gene Mutation Symptoms The Catechol-O-Methyltransferase (COMT) gene is essential for breaking down certain brain chemicals called catecholamines, which include dopamine, norepinephrine, and epinephrine. These chemicals act as neurotransmitters—messengers that help nerve cells communicate. COMT ensures that their levels remain balanced, preventing overstimulation or depletion that could affect brain function. However, changes in the COMT […]
Optimizing Medication for ADHD The US still needs to focus more on Mental Health. A huge number of people still don’t receive mental health medication, and many experience adverse drug effects due to the trial-and-error in medication. Thus, the FDA itself has labelled some mental health drugs for genome-based administration. Knowing your genetic makeup helps […]
CPIC: The Clinical Pharmacogenetics Implementation Consortium In today’s rapidly evolving healthcare environment, personalised medicine is becoming increasingly important. One of the most crucial advancements in this area is the implementation of pharmacogenetics, the study of how genetic variations affect an individual’s response to drugs. To facilitate the practical application of pharmacogenetics in clinical settings, the […]