RPh Gen Lab offers a PGx testing kit that reduces Trial and Error from your medication. Get insights into your genetic makeup and see how your body may react to 240+ medications with this drug DNA test. Our CLIA-accredited PGx testing report can help you and your doctor select optimal medication that increases drug efficacy and lowers adverse drug reactions. Let your pharmacogenomics test be the guide in:
Selecting medications best suited to your genetic makeup.
Adjusting dosages based on your metabolism.
Narrowing down medications by removing the trials.
Our reports are as clear as a well-written guide – with clear, actionable warnings about certain medications and their substitutes.
There is a complete table of FDA-labeled medications containing pharmacogenomic information. Based on the biomarker information, some labels also share required actions to be taken when consuming/administering these drugs. Here is the link to the Pharmacogenomic Biomarkers table shared by the FDA.
PGx Testing Covered Genes
While CLIA-Accredited PGx testing at RPh Labs can look at several critical genes and give insights into how your body may respond to 240+ medications. Some of the most commonly tested genes include:
1
CYP450 Enzymes
Such as CYP2C19, CYP2D6, and CYP3A4, are involved in metabolizing a wide range of drugs, including antidepressants, painkillers, and blood thinners.
2
VKORC1 and CYP2C9
CYP2C9, a liver enzyme from the cytochrome P450 family, metabolizes 15–20% of drugs, including anticoagulants, NSAIDs, statins, and antiepileptics. VKORC1 regulates the vitamin K cycle, crucial for blood clotting. Genetic variations in both CYP2C9 and VKORC1 affect warfarin metabolism and dosing, emphasizing the role of pharmacogenetic testing in personalized medicine.
3
TPMT
TPMT is an enzyme responsible for metabolizing thiopurine drugs, such as azathioprine, mercaptopurine, and thioguanine, and is crucial for determining the safe use of chemotherapy and immunosuppressive drugs.
4
HLA Genes
Responsible for hypersensitivity reactions to medications, such as carbamazepine, allopurinol, and abacavir.
Who Should Use Genetic Testing For Medication
The Pharmacogenomic Testing Kit of the Rph Labs is appropriate for:
Patients on new drugs want to know how certain medication affects their health.
Patients who have adverse drug reactions or side effects.
Those who have had a history of not responding well to some drugs.
Hospitals and caregivers who are interested in offering precision medicine solutions to their patients.
Anyone who is concerned with a healthy lifestyle and wants to explore how their DNA reacts with certain drugs.
With the pharmaceutical genetic testing, you gain knowledge, confidence, and peace of mind, making medication management, along with your healthcare provider, confidential.
How Does the PGx Testing Kit Work?
Sample Collection
RPH Labs collect a small DNA sample using the swab included in the PGx Testing Kit. No blood draw is needed, like in conventional testing, making the process quick and non-invasive.
Secure Analysis
After collecting the sample, Rph Labs, a certified pharmacogenomics testing lab's experts conducts advanced pharmacogenomic testing using state-of-the-art technology.
Personalized Report
After processing, we generate a medical report detailing on how your body react to specific 240+ medications. Only you can access or download this report because Rph Labs is HIPAA compliant.
Actionable Insights
Our drug DNA report is practical and easy to understand for anyone. You can share it directly with your doctor, enabling them to make informed decisions about your prescriptions treatment.