Our immune system maintains self-tolerance. Tacrolimus, commonly available under the brand name Prograf, is an immunosuppressant medication primarily used to prevent organ rejection after transplantation (kidney, liver, heart, lung). It works by suppressing the immune system, which helps prevent the body from attacking the transplanted organ. Let’s have a look at Tacrolimus mechanism of action, […]

Selective serotonin reuptake inhibitors mnemonic (SSRIs) are prescription medications belonging to the drugs category used to treat a variety of mental health conditions, including depression, anxiety, and obsessive-compulsive disorder (OCD). The following are some uses: Uses of SSRIs: Major depressive disorder Generalized anxiety disorder (GAD) Panic disorder Obsessive-compulsive disorder (OCD) Social anxiety disorder Posttraumatic stress […]

Benzodiazepines, commonly known as benzos, are a class of psychoactive drugs primarily used for their sedative, anxiolytic (anxiety-reducing), muscle relaxant, and anticonvulsant properties. Benzodiazepines, like Xanax (alprazolam) and Valium (diazepam) function by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA_A receptor, leading to a calming effect on the nervous system. The […]

An overactive bladder (OAB) is a condition characterized by a frequent and urgent need to urinate, often accompanied by incontinence. It severely hampers everyday daily life due to the significant discomfort and disturbing social, work, or personal activities. Though many pharmaceuticals are available for relief from symptoms caused by an overactive bladder, some may not […]

Vraylar (Cariprazine) is an atypical antipsychotic medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of bipolar disorder and schizophrenia. It primarily works by modulating dopamine and serotonin activity in the brain. Before we discuss Cariprazine Bipolar Connection, here is a glimpse into how this drug works, its indications, active ingredients, […]

Medical errors refer to preventable mistakes in healthcare that can cause harm to patients. These errors can occur in diagnosis, treatment, medication administration, surgery, or even during routine medical procedures. According to a study shared by the National Library of Medicine, about 400,000 hospitalized patients experience avoidable medical errors while the same avoidable medical errors […]

Seroquel is an atypical antipsychotic drug. It is given for the treatment of mental disorders, primarily for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. When taken appropriately, it preserves the chemicals within the brain to smooth the symptoms. In overdose, though, Seroquel can be fatal, and its cure requires urgent medical attention […]

The connection between the human genome (complete set of your DNA) and medications has been a matter of study for years, however, due to limited evidence, healthcare providers have been cautious in adopting genome-based diagnostics. To ascertain the evidence needed to make these genome-based tests of clinical value, a workshop hosted by the Institute of […]

The SLCO1B1 gene encodes the organic anion (group of compounds that include fatty acids, bile acids, and anionic drugs) transporting polypeptide 1B1 (OATP1B1), a liver-specific transmembrane receptor responsible for the sodium-independent uptake of various endogenous compounds (growing or originating from within an organism), including bilirubin, 17-beta-glucuronosyl estradiol, and leukotriene C4. Additionally, OATP1B1 plays a crucial […]