Vraylar (Cariprazine) is an atypical antipsychotic medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of bipolar disorder and schizophrenia. It primarily works by modulating dopamine and serotonin activity in the brain. Before we discuss Cariprazine Bipolar Connection, here is a glimpse into how this drug works, its indications, active ingredients, […]
Atomoxetine vs Adderall Atomoxetine (Strattera) belongs to the selective norepinephrine reuptake inhibitors (SNRIs) category. It solely treats ADHD (attention deficit hyperactivity disorder) in children (6 years and older), teenagers, and adults, while Adderall belongs to ‘stimulants’ and is mostly used to treat ADHD, it also treats Narcolepsy (daytime sleep disorder), stimulates psychological and cognitive functions […]
Avoidable Medical Errors: Causes, Consequences, & Solutions Medical errors refer to preventable mistakes in healthcare that can cause harm to patients. These errors can occur in diagnosis, treatment, medication administration, surgery, or even during routine medical procedures. According to a study shared by the National Library of Medicine, about 400,000 hospitalised patients experience avoidable medical […]
Seroquel Overdose: Causes, Symptoms and Treatments Seroquel is an atypical antipsychotic drug. It is given for the treatment of mental disorders, primarily for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. When taken appropriately, it preserves the chemicals within the brain to smooth the symptoms. In overdose, though, Seroquel can be fatal, and […]
Genome-Based Diagnostics The connection between the human genome (complete set of your DNA) and medications has been a matter of study for years, however, due to limited evidence, healthcare providers have been cautious in adopting genome-based diagnostics. To ascertain the evidence needed to make these genome-based tests of clinical value, a workshop hosted by the […]
The SLCO1B1 gene encodes the organic anion (group of compounds that include fatty acids, bile acids, and anionic drugs) transporting polypeptide 1B1 (OATP1B1), a liver-specific transmembrane receptor responsible for the sodium-independent uptake of various endogenous compounds (growing or originating from within an organism), including bilirubin, 17-beta-glucuronosyl estradiol, and leukotriene C4. Additionally, OATP1B1 plays a crucial […]
What is a PGx Test and Genomic Medicine? The history of medication has been working around trials and errors. This not only has proven to sometimes aggravate the condition but even deaths have occurred due to the trials in medications. There has always been a need for medications that don’t affect individuals in a way […]
CYP2B6 Intermediate Metabolizers’ Response to Medications The role of the CYP2B6 enzyme in drug metabolism is crucial, especially for individuals undergoing HIV treatment. CYP2B6 intermediate metabolizers, who possess a moderate level of enzyme activity due to genetic polymorphisms, face unique challenges when prescribed HIV medications metabolized by this enzyme, such as efavirenz. Efavirenz, a cornerstone […]
Does PGx Help in Providing Practical Cardiovascular Medicine Pharmacogenomics (PGx) is transforming cardiovascular medicine by enabling personalized treatment approaches based on a patient’s genetic profile. In particular, PGx is helping cardiologists optimize the use of antiplatelet, anticoagulant, and beta-blocker therapies in patients with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI). While numerous […]
Tardive Dyskinesia Treatment Guidelines: An Overview Tardive dyskinesia (TD) is a neurologic disorder involving involuntary, repetitive body movements that often result from long-term use of certain medications, particularly antipsychotics and other dopamine receptor-blocking agents. These movements may include the tongue, lips, face, trunk, and extremities and significantly impact a patient’s quality of life. Managing tardive […]