COMT Gene Mutation Supplements To understand COMT Gene Mutation Supplements, it’s important to first know the COMT gene and its mutation. The COMT (catechol-O-methyltransferase) gene encodes an enzyme (COMT enzyme) responsible for breaking down catecholic compounds in the body, including neurotransmitters like dopamine, norepinephrine, and epinephrine, as well as hormones such as estrogen. By methylating […]