Cytochrome P450 2D6, commonly referred to as CYP2D6 is one of the key enzymes in the liver responsible for metabolizing approximately 25% of clinically used medications. Ultrarapid metabolizers have an increased rate of converting prodrugs, such as codeine and tramadol, into their active forms (morphine and O-desmethyltramadol, respectively). This rapid conversion can lead to a […]
Attention-Deficit/Hyperactivity Disorder (ADHD) affects millions in the United States. According to the CDC, approximately 6 million children between the ages of 3–17 have been diagnosed with ADHD, while millions of adults also live with this condition. Treating ADHD effectively often involves trial and error with various medications and dosages, leading to prolonged discomfort for patients […]
Verzenio (abemaciclib) is a prescription medication used to treat advanced or metastatic breast cancer. Cancer cells grow and move to other organs, this medicine works by stopping the growth of cancer cells. It is a cyclin-dependent kinase (CDK) 4/6 inhibitor, meaning it blocks the activity of proteins that control cell growth, which can help slow […]
Most people are unaware of the fact that the FDA has labeled certain medications as they can affect individuals differently. Pharmacogenomics tests often known as PGx tests provide insights into your genetic makeup that help doctors tailor medications and reduce the trial-and-errors, especially in areas like mental health, where individual responses to drugs can vary […]